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Amino Acid Representation in Human Body and in Human Myoglobin based on 2009 research
 
Essential amino acids in boldface large size type; controversially essential amino acids in boldface normal size type; non-essential amino acids in normal type; amino acids related to each other via ability of body to manufacture one amino acid from another share the same row colors; amino acids not related to other amino acids through ability of amino acids to produce each other in white background rows; e=essential, ne=nonessential, e?=essential but controversial; ne?=nonessential but controversial.
 
Column K = H divided by A molec wt; H times H divided by A molec wt.
Column L = F (essential only) divided by C;

Protein
name
A
%
molec
wt in
body;
 
occur
rence
in body
B

mg/
kg
req
in
body
C
mg/
kg
req
in
body
as
%
of
total
essential
amino
acid
mg/kg
requir
ements
D
mg/kg
requi
rement
in body
as %
of total
(essen
tial, non-
essent
ial
both)
amino
acid
mg/kg
require-ments or
sugge
sted
intake
E
number
pieces
amino
acid
in myo-globin;
this times
molec wt/
10
F
number
pieces
amino
acid in myo-
globin
as perce
ntage
of total pieces
(79) of
esse-
ntial
amino
acid in
myo-
globin;
 
as percentage
of total
pieces of ALL (153) amino acids in myoglobin
G
mole
cular
wt of amino
acid
g/
mol
/10
H
mole
cular
wt of amino
acid as perce
ntage
of myo-
globin
mole
cular weight
I
internal
bio-synthesis
ingredients
& methods
J
notes
K
(see
notes
for
expla
nat
ion)

 
L
(see
notes
for
expla
nat
ion)
M
N
Glutamate 
 
ne
6.2
6.3



14
(210)

 
9.2
15
10.6
1glutamine+water,
2 nacglu + water
3 alpha-ketoglutaric acid + nadph (nicotinamide) + transanimase
4 alpha-ketoglutaric acid + any amino acid + transanimase
5 1-pyrroline-5-carboxylate + co-enzyme Nad a nicotinamide 
+ water + enzyme aldh4 (aldehyde  dehydrogenase) 
6 Formiminoglutamic acid + folic acid +
protein enzyme ftcd  (Formiminotransferase cyclodeaminase)
7 ornithine
8 arginine
excitatory neurotransmitter precursor to gaba

1.7
18.0



Glutamine
ne
4.1?
4.2



07
(105)
4.6
15
5.3
1 glutamate or glutamic acid its precursor
2 glutamate and NH4 (ammonia) by the product of the glnA gene (GS);
3 alpha-ketoglutarate combined with ammonia

1.3
6.9



Proline
ne
4.2
5.2
05
(60)
3.3 12 3.0
1 glutamic acid + pyrroline carboxylate reductase

0.7
2.1



Arginine
e
4.7
5.1



02
(34)
2.5
1.3
17
1.7
1 citrulline or citruline (which can be produced by arginine itself) which is derived from  ornithine via catabolism of proline or glutamine/glutamate (bidirectional pathways)
2 from citrulline which is from asymmetric dimethylarginine (ADMA) via DDAH

0.4
0.6



Alanine
ne
9.0
7.8



12
(108)
total this group:
40
(517)
7.8
09
5.5
1 citrulline or citruline (which can be produced by arginine itself) which is derived from  ornithine via catabolism of proline or glutamine/glutamate (bidirectional pathways)
2 from citrulline which is from asymmetric dimethylarginine (ADMA) via DDAH

0.6
3.3



Aspartate 
ne
5.4?
5.3
08
(104)
5.2 13 5.3
1 from oxaloacetate by aminotransferases

1.0
5.3



Asparagine 
ne
4.4
4.3



03
(39)
 
total this group:
11
(143)
2.0 13 2.0
1 aspartate via asparagine synthetase

0,5
0.9



Glycine
ne
7.5
7.2



15
(120)
9.8
08
6.1
1 serine via two different hydroxy-methyl-transferase enzymes

0.8
5.0



Serine
ne
7.1
6.8



07
(77)
 
total this group:
22
(197)
4.6
11
3.9
1 3-phosphoglycerate +aminotranferase + phosphoserine phosphatase
2 glycine + hydroxymethyltransferase

0.5
2.1



Leucine 
ne?
7.5
9.1
39
21.2

17
(191)
21.5
11.1
13
9.6
1 keto acid a-ketoisovalera to,
2 keto acid a-isopropylmalate,
3 keto acid - isopropylmala to,
4 keto acid a-ketoisocaproate (KIC)

1.3
12.3
1.0


Phenylalanine
e
3.5
3.9
25
(incl
tyro
sine)
13.6
(inc
tyro
sine)

07
(119)
8.9
4.6
17 6.0 No human biosynth found
1.7
10.3
0.7


Tyrosine
ne
3.5
3.2



02
(36)
 
total this group:
09
(155)
1.3
18
1.8
1 phenylalanine  'if the essential amino acid precursor is not available, (tyrosine is) also unavailable'.

0.5
0.9



Lysine 
e?
7.0
5.9
30
16.3

20
(300)
25.3
13.1
15
15.2
1 ammonium chloride + urea in intestine = at least 37% of 30 mg per kg requirement

2.2
33.0
1.6


Valine 
e
6.9
6.6
26 14.1
07
(84)
8.9
4.6
12
4.2
no report of human bio synthesis

0.6
2.6
0.6


Threonine 
e
6.0
5.9
15 8.2
04
(48)
5.1
2.6
12 2.4  no report of human bio synthesis
0.4
9.6
0.6


Isoleucine 
e
4.6
5.3
20
 
10.9

08
(104)
10.1
5.2
13 5.3  no report of human biosynthesis
1.2
6.1
0.9


Methionine 
e?
1.7
2.3
15
(incl
cyst
eine)
8.2
(incl
cyst
eine)

03
(45)
3.8
2.0
15
2.3
1: vitamin B1 + vitamin B 1 z-dependent
5-methyltetrahydrofolate-homocysteine
methyltransferase (MTR enzyme) + homocysteine
2: metallo-enzyme  betaine-homocysteine methyltransferase + betaine + homocysteine

1.4
3.1
0.5


Cysteine
ne
2.8
1.9



01
(12)
 
total this group:
04
(57)
0.7
12
0.6
1 serine
2 homocysteine
3  serine + homocysteine
4 methionine only 'if the essential amino acid precursor is not available, (cysteine is) also unavailable'. Thus 'not really accurate' that it is non-essential.

0.2
0.1



Histidine
e?
2.1
2.3
10
5.4

09
(144)
11.4
5.9
16
7.3
1 hydrolysis of proteins

3.5
25.4
2.1


Tryptophan
e
 
1.1
1.4
04
2.2

02
(40)
2.5
1.3
20
2.0
1 90% tryptophan synthesized in intestines, this isolated report disputed by everyone
1.8
3.6
1.1


Totals

essential
only:
184;


153
(1980)
























 
 
Molecular weight in human body as percentage of total molecular weight of amino acids in human body:
 http://www.jadenutra.com/aminoacids.html;
occurrence in human body, percentage:
http://www.molecularwiki.org/Amino_acids_synthesis;
mg per kg body weight daily requirement for 'essential' amino acids:
http://www.zimbio.com/Acaiberry/articles/3763/Essential+amino+acid;
composition of myoglobin:
http://www.aw-bc.com/mathews/ch07/c07emhp.htm, http://www.aw-bc.com/mathews/ch05/fi5p14.htm;
molecular weights of amino acids:
 http://www.webqc.org/aminoacids.php
 
@2009 David Virgil Hobbs