Creatine myoglobin creatine-kinase micrograms per gram in human flesh and blood

Data/Estimates Table showing creatine myoglobin creatine-kinase micrograms per gram in human flesh and blood (table is below intro text)

My commentary re the production of this table (first version finished June 26 '09):

I felt I had to improve my understanding regarding, looking at substances the body uses to deal with exercise, specifically myoglobin (oxygen storage/transport protein), creatine (energy storage transport and release amino acid), and various types of creatine kinases (enzymes such as CK-BB, CK-MB, CK-MM, Mito-CK that operate on creatine).

I needed to improve my understanding regarding what proportion of the total of all of these, each substance composing the total represents.

A super snack that increases the amount of work the body can do befor becoming fatigued, would IMHO have positive cardiac health effects. I did not feel comfortable trying to cook up said miraculous super-snack for consuming prior to exercise, without getting such an understanding.

I felt afraid of over-emphasizing or under-emphasizing some part of the whole. I felt that it would be easy to over or under emphasize for example a type of creatine kinase, or creatine itself, or myoglobin.

The different types of creatine kinase are composed differently in terms of the representation of various amino acids. The amino acid representation in creatine kinase is completely different compared to the molecular structure of creatine.

I was shocked that I had to put together this table you can see on this page below this text, from a million different sources, making estimates for values in table cells based on data obtained for other table cells.

I expected that this kind of table and the info I've gathered into it would be easy to find and would already have been created.

I estimate that the world's incompetence in this matter of negligence re producing said table, has to do with the error of failing to appreciate getting a good solid grasp of the overall big picture before delving into details. Fact is when you meddle with details you can end up disturbing and changing the overall big picture itself.

Nutritionists seem to forget that people have a limited amount of space in their stomach and putting one thing in the stomach gets in the way of putting another thing in the stomach. Similarly software developers produce software as if the assumption was that, the software user has as much time and mental energy to put into the software as the developer has been putting into it.

It was repeatedly annoying to, in the process of doing the hard work of researching out the table you can see below, continually encounter on the internet these persons making reports, who used measurements such as blah per liter, when the only way in which the blah per liter figure can be related to figures in other reports and studies, is to know certain hidden facts regarding the density and mass of blah-- yet at the same time the authors of the report do nothing to tell you the info you need to know about blah or point you in a direction where you could find such info.

Said annoyancing writers kept using irritating mysterious measurements such as U/liter, moles, umole, gmole, IU, etc etc. For sure obfuscation and pedantic pretentiousness are alive and well out there in internet-land.

The table I finally put together has allowed me to estimate that looking at myoglobin and creatine and the creatine kinases in the body all put together as a whole: myoglobin is in terms of milligram weight 72% of the total whole; creatine-kinase-MM is 20% of the total whole; creatine is 7% of the total whole; and, creatine-kinase-MB is 1% of the total whole.

Data/Estimates Table showing creatine myoglobin creatine-kinase micrograms per gram in human flesh and blood

range (where available),

weight of substance

as percent of weight

range,

mean/average

in percent,

weight of substance

as percent of weight

of tissue substance

embedded in

x 10,000

range,

mean/average

in percent,

weight of substance

as percent of weight

of tissue substance

embedded in,

x 10,000

weight of substance

as percent of weight

of tissue substance

embedded in,

x 10,000;

Above figure as percent of total of above

figure for all rows

my estimate for humans

my estimate, for human,

In body 60% is phospho

creatine; 40% is free

of body's creatine pool

In humans half the daily

creatine needs supplied

arginine, glycine, and methionine

120-140 g creatine stored

in body, 98% in muscle

70% is phosphocreatine

replaced at rate of 20mg/kg/day;

used by 100% of rugby and weightlifters

my estimate for humans,

(total of rows below)

constitutes 15.0000%

of 'muscle cytoplasmic

my estimate for humans,

creatine and creatine-

kinase both decline in rats

my estimate for humans,

'expressed at low

levels in all tissues little clinical significance'

mainly produced by brain & smooth muscle

books.google.com/books?isbn=0683302736...

strange statement that myoglobin is 2.1% of human skeletal muscle:

more believable report re myoglobin representation

statement that creatine-kinase represents 15% of 'muscle cytoplasmic protein'

@2009 David Virgil Hobbs